24 Nov

15:00:00
Fulham v Southampton
Craven Cottage, London, United Kingdom
. Premier League

1 Dec

15:00:00
Southampton v Manchester United
St. Mary's Stadium, Southampton, United Kingdom
. Premier League

5 Dec

20:00:00
Tottenham Hotspur v Southampton
Tottenham Hotspur Stadium, London, United Kingdom
. Premier League

8 Dec

15:00:00
Cardiff v Southampton
Cardiff City Stadium, Cardiff, United Kingdom
. Premier League

15 Dec

15:00:00
Southampton v Arsenal
St. Mary's Stadium, Southampton, United Kingdom
. Premier League

22 Dec

15:00:00
Huddersfield v Southampton
John Smith's Stadium, Huddersfield, United Kingdom
. Premier League

26 Dec

15:00:00
Southampton v West Ham
St. Mary's Stadium, Southampton, United Kingdom
. Premier League

29 Dec

15:00:00
Southampton v Manchester City
St. Mary's Stadium, Southampton, United Kingdom
. Premier League

1 Jan

15:00:00
Chelsea v Southampton
Stamford Bridge, London, United Kingdom
. Premier League

12 Jan

15:00:00
Leicester City v Southampton
King Power Stadium, Leicester, United Kingdom
. Premier League

19 Jan

15:00:00
Southampton v Everton
St. Mary's Stadium, Southampton, United Kingdom
. Premier League

30 Jan

19:45:00
Southampton v Crystal Palace
St. Mary's Stadium, Southampton, United Kingdom
. Premier League

2 Feb

15:00:00
Burnley v Southampton
Turf Moor, Burnley, United Kingdom
. Premier League

9 Feb

15:00:00
Southampton v Cardiff
St. Mary's Stadium, Southampton, United Kingdom
. Premier League

23 Feb

15:00:00
Arsenal v Southampton
Emirates Stadium, London, United Kingdom
. Premier League

27 Feb

19:45:00
Southampton v Fulham
St. Mary's Stadium, Southampton, United Kingdom
. Premier League

2 Mar

15:00:00
Manchester United v Southampton
Old Trafford, Manchester, United Kingdom
. Premier League

9 Mar

15:00:00
Southampton v Tottenham Hotspur
St. Mary's Stadium, Southampton, United Kingdom
. Premier League

16 Mar

15:00:00
Watford v Southampton
Vicarage Road, Watford, United Kingdom
. Premier League

30 Mar

15:00:00
Brighton v Southampton
Amex Stadium, Brighton, United Kingdom
. Premier League

6 Apr

15:00:00
Southampton v Liverpool
St. Mary's Stadium, Southampton, United Kingdom
. Premier League

13 Apr

15:00:00
Southampton v Wolves
St. Mary's Stadium, Southampton, United Kingdom
. Premier League

20 Apr

15:00:00
Newcastle United v Southampton
St. James' Park, Newcastle, United Kingdom
. Premier League

27 Apr

15:00:00
Southampton v Bournemouth
St. Mary's Stadium, Southampton, United Kingdom
. Premier League

4 May

15:00:00
West Ham v Southampton
London Stadium, London, United Kingdom
. Premier League

12 May

15:00:00
Southampton v Huddersfield
St. Mary's Stadium, Southampton, United Kingdom
. Premier League